Calculate a complete toxicity analysis — calculate_toxicity

Calculates weighted toxicity scores (WTS).

Usage

calculate_toxicity_analysis(
  trial_data,
  n_simulations,
  unacceptable_rel_increase = 0.5,
  k_uncertainty = 5,
  soc_weights = c(`Gastrointestinal disorders` = 1.2,
    `Blood and lymphatic system disorders` = 1.6,
    `General, metabolic, and other disorders` = 1.3, `Dermatologic disorders` = 1.1,
    `Infections and infestations` = 1.6,
    `Respiratory, thoracic and mediastinal disorders` = 2.5)
)

Arguments

trial_data: A list containing the toxicity data.
n_simulations: An integer for the number of simulations.
unacceptable_rel_increase: A number for the unacceptable increase limit.
k_uncertainty: A number for the uncertainty constant.
soc_weights: The default weights for toxicity categories

Value

A list containing the results.