This dataset contains simulated toxicity data and quality of life (QoL) scores
from the PALOMA‑2 randomized clinical trial (palbociclib plus letrozole in
hormone receptor–positive, HER2–negative advanced breast cancer). It includes
both any‑grade (G1–4) and severe (G3–4) adverse events. Patient‑reported QoL
scores are stored in the qol column. The dataset provides the number of
patients per trial arm. Please refer to the accompanying documentation or
vignette for details on how QoL scores are defined and interpreted.
Format
A data frame with X rows and Y variables:
- EventName
Name of the adverse event.
- SystemOrganClass
System organ class for the adverse event.
- Incidence_G1_4_Control
Incidence (%) of any‑grade (G1–4) toxicity in the control arm.
- Incidence_G1_4_Experimental
Incidence (%) of any‑grade (G1–4) toxicity in the experimental arm.
- Incidence_G3_4_Control
Incidence (%) of severe (G3–4) toxicity in the control arm.
- Incidence_G3_4_Experimental
Incidence (%) of severe (G3–4) toxicity in the experimental arm.
- qol
Numeric QoL score associated with each adverse event.
- N_patients
Named numeric vector with the number of patients per trial arm.